Containing Farnesyltransferase Inhibitors

Papers needed to answer some questions: BMCLLi, Q. et al. (2004) ‘Design, synthesis, and activity of 4-quinolone and pyridone compounds as nonthiol-containing farnesyltransferase inhibitors’, BioorganicMedicinal Chemistry Letters, vol. 14, pp. 5367–70. Biochemistry paper below: Strickland, L. et al. (1998) ‘Crystal Structure of Farnesyl Protein Transferase Complexed with a CaaX Peptide and Farnesyl DiphosphateAnalogue’ Biochemistry, vol. 37, pp. 16601–11

Originally posted 2018-07-20 14:53:17. Republished by Blog Post Promoter